Search results for "Protein microspheres"
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Direct formation of highly tunable and biocompatible protein microparticles
Highly tunable protein microspheres for drug delivery
2019
Traditionally protein aggregation has been related to several neurodegenerative diseases, however in the past few years there has been a grown interest to use them as biomaterials. Among the very broad range of different amyloid structures a special focus has been developed on protein particulates, spherical protein aggregates formed at a pH near the isoelectric point of the protein they are made of, whose radius ranges from hundreds of nm to few um. They are a generic feature for all globular proteins and besides, they have never been related to any disease. Among the years different methods for the functionalization of amyloid fibrils or microspheres have been unravelled, but normally the…